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| C_ID | Metabolite Name | Activity Category | Biological Activity (Function) | Target Species | Reference |
|---|---|---|---|---|---|
| C00001650 | Lappaconitine | Antipyretic | Antipyretic | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |
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| C00001650 | Lappaconitine | Pneumotoxic | toxic doses produce respiratory paralysis | Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter19 | |
| C00001650 | Lappaconitine | Toxic | have a direct action upon the heart, often terminating in ventricular fibrillation | Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter19 | |
| C00001650 | Lappaconitine | Toxic | highly toxic though 40 times less toxic than aconitine intravenously | Mus musculus | Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter19 |
| C00001650 | Lappaconitine | Analgesic | Analgesic | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |
|
| C00001650 | Lappaconitine | Antiarrhythmic | Cardiovascular activity, antiarrhythmic | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |
|
| C00001650 | Lappaconitine | Antiedemic | Anti-inflammatory, formaldehyde edema model | mus | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |
| C00001650 | Lappaconitine | Anti-inflammatory | Anti-inflammatory, modified Tan and Berridge method | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |
|
| C00001650 | Lappaconitine | Antioxidant | Antioxidant, DPPH scavenger | Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yang, et al., Acta Pharmaceutica Sinica(Yaoxue Xuebao), 35, (2000), 208. Shaheen, et al., Phytochemistry, 66, (2005), 935. |