C_ID | Metabolite Name | Activity Category | Biological Activity (Function) | Target Species | Reference |
---|---|---|---|---|---|
C00003741 | Betulinic acid | Antimalarial | Antimalarial inactive | Plasmodium falciparum | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
C00003741 | Betulinic acid | Antituberculotic | Antibacterial | Mycobacterium tuberculosis | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
C00003741 | Betulinic acid | Antitumor | Antineoplastic, W256 Walker sarcoma | rat | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
C00003741 | Betulinic acid | Antiallergic | Cytotoxic, COX-2 inhibitor | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
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C00003741 | Betulinic acid | Anticancer | Cytotoxic, A549 non-small cell lung cancer cells | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
|
C00003741 | Betulinic acid | Anticancer | Cytotoxic, B16(F-10) (moved) melanoma cells | mouse | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |
C00003741 | Betulinic acid | Anticancer | Cytotoxic, K562 hmn leukemia cells | Lee, et al., Planta Med, 69, (2003), 1051. Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Deachathai, et al., Phytochemistry, 66, (2005), 2368. Gu, et al., Planta Med, 70, (2004), 509. Kinghorn, et al., Planta Med, 70, (2004), 691. Carcache-Blanco, et al., Journal of Natural Products, 66, (2003), 1197. Mutai, et al., Phytochemistry, 65, (2004), 1159. Suksamrarn, et al., Chem Pharm Bull, 54, (2006), 535. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Wang, et al., Chinese Pharmaceutical Journal(Zhongguo Yaoxue Zazhi), 29, (1994), 268. Xiong, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 18, (1993), 486. Guo, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 23, (1998), 546. |