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| C_ID | Metabolite Name | Activity Category | Biological Activity (Function) | Target Species | Reference |
|---|---|---|---|---|---|
| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Cytotoxic | Cytotoxic, HUVEC hmn umbilical vein endothelial cells | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
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| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Phytoalexin | Phytoalexins and inducers of nitrogen fixing bacteria | Cladosporum cucumerinum | Wang,Phytochem.,28,(1989),2323 |
| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Anticancer | Cytotoxic, HCT116 hmn colorectal cancer cells | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
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| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Anticancer | Cytotoxic, KB hmn nasopharyngeal carcinoma cells | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
|
| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Antineoplastic | Antineoplastic inactive, KB, LNCaP, Lu1 and P388 | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
|
| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Antineoplastic | Antineoplastic, horrow fiber assay | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
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| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Antiviral | Antiviral, no explanation of virus species | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
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| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Cytotoxic | Cytotoxic, hTERT-RPE1 hmn telomerase reverse transcriptase-retinal pigment epithelial cells | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |
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| C00004705 | Casticin 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone Quercetagetin 3,6,7,4'-tetramethyl ether Vitexicarpin 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one | Anticancer | Cytotoxic, Col2 hmn colorectal cancer cells | Chen, Liu, et al., Determination of Effective Components in Traditional Chinese medicines, People's Medical Publishing House, Beijing, (2009). Diaz, et al., Journal of Natural Products, 66, (2003), 865. Ono, et al., Journal of Natural Products, 65, (2002), 537. Brown, et al., Phytochemistry, 64, (2003), 303. Sun, et al., Brief Handbook of Natural Active Compounds, Medicinal Science and Technology Press of China, Beijing, (1998). Chinese Materia Medica Editing Committee of the National Chinese Medicine and Pharmacology Bureau, Chinese Materia Medica (ZHONG HUA BEN CAO), Vol.1-Vol.30, Shanghai Science and technology Press, Shanghai, (1999). Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Edited by Jiangsu New Medicinal College, Chinese Medicine Dictionary, Shanghai Science and technology Press, Shanghai, (1979). Zeng, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 21, (1996), 167. |