C_ID | Metabolite Name | Activity Category | Biological Activity (Function) | Target Species | Reference |
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C00007057 | Licochalcone A | Antioxidant | Antioxidant, free radical scavenger, no description on type of free radical | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Antithrombotic | Anticoagulant | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Hemostatic | Antihemolytic, H2O2-induced hemolysis of RBC | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Anticancer | Cytotoxic, HT1080 hmn fibrosrcoma cells | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Anticancer | Cytotoxic, inhibits TPA-induced 32P combines with phospholipid in HeLa cells | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Antiedemic | Anti-inflammatory, ear edema, induced by TPA | mus | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Antiedemic | Anti-inflammatory, ear edema, induced by TPA | mus | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Anti-HIV | Anti-HIV, inhibits HIV-induced formation of giant-cells | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Antimalarial | Antimalarial | Plasmodium falciparum 3D7 | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Antimalarial | Antimalarial | Plasmodium falciparum Dd2 | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Antioxidant | Antioxidant | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Antiallergic | Antiallergic | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
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C00007057 | Licochalcone A | Antibacterial | Antibacterial | Bacillus subtilis | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Antibacterial | Antibacterial | Staphylococcus aureus | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Antibacterial | Antibacterial | Staphylococcus aureus methicillin-resistant strain | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |
C00007057 | Licochalcone A | Anticancer | Antineoplastic, papillary carcinoma | Yin, et al., Modern Study of Chinese Drugs and Clinical Applications (1), Xueyuan Press, Beijing, (1993). Xu, et al., China Journal of Chinese Materia Medica(Zhongguo Zhongyao Zazhi), 22, (1997), 679. Buckingham(Executive Editor), Dictionary of Natural Products, Chapman & Hall, 1994, Vol1-7 1995, Vol8 1996, Vol9 1997, Vol10 1998, Vol11. Hatano, et al., Chem Pharm Bull, 36, (1988), 2286. Hatano, et al., Chem Pharm Bull, 37, (1989), 3005. Shibata, et al., Planta Med, 57, (1991), 221. Okada, et al., Chem Pharm Bull, 37, (1989), 2528. Matsuno, et al., Biochem Pharmacol, 36, (1987), 1613. Chem Abstr, 122, (1995), 51291r. Hatano, et al., Chem Pharm Bull, 36, (1988), 2092. Chem Abstr, 118, (1993), P124293x. Chen, et al., Antimicrob Agents Chemother, 38, (1994), 1470. Yoon, et al., Chem Pharm Bull, 53, (2005), 694. |